Signs and symptoms of lung cancer may include A new cough that doesnt go away Coughing up blood even a small amount Shortness of. The most common symptoms of lung cancer are A cough that does not go away or gets worse Coughing up blood or rust-colored sputum spit or phlegm. What Are the Symptoms of Lung Cancer Coughing that gets worse or doesnt go away. You may feel pain in your chest especially when breathing deeply coughing or laughing Generalized symptoms of lung cancer include. In the early stages lung cancer symptoms may include chest pain chronic cough breathing issues and weight loss..